Journal: iScience

Article Title: Experience and behavior modulate piriform cortex odor representation in freely moving mice

doi: 10.1016/j.isci.2026.115897

Figure Lengend Snippet: Recording and odor presentation paradigm (A) Schematic of the recording apparatus and paradigm. Ten trials of six odorants (BZ = benzaldehyde, C4 = butyraldehyde, E4 = ethyl butyrate, H2 = 2-heptanone, LL = linalool, DP = dimethyl pyrazine) were presented over five consecutive days of passive odor experience while neuronal activity was continuously recorded via miniscope. (B) Example GRIN lens implantation site from one animal in PC; annotated to show the primary layers, scale bar in the bottom left is 250 μm. (C) Example calcium traces from ten neurons recorded over 400 s at the start of a recording session. (D) Mean PID trace (black line, gray bars denote SD) taken from ten presentations of E4 during field presentations. The PID intake port was placed at the back of the chamber opposite the odor port. (E) Individual PID traces from odor pulses as in (D), but with the intake port placed directly in front of the olfactometer output line; black line indicates the first trial and the red line indicates last trial.

Article Snippet: GRIN lens , Inscopix , 0.5 × 6.1 mm lens.

Techniques: Activity Assay